Evaluation of S100B in cerebrospinal fluid as a potential biomarker for neurological diseases in calves
نویسندگان
چکیده
S100B in cerebrospinal fluid (CSF-S100B) was measured in calves with 20 neurologic and 21 non-neurologic diseases to clarify its utility as a biomarker for neurologic diseases. The median CSF-S100B value in the neurologic disease group (43.0 ng/ml) was significantly higher than that in the non-neurologic disease group (10.2 ng/ml). As CSF-S100B levels in calves with neurologic diseases widely differed, the utility of CSF-S100B as a diagnostic marker for neurologic diseases in cattle remains inconclusive.
منابع مشابه
NOTE Internal Medicine Evaluation of S100B in cerebrospinal fluid as a potential biomarker for neurological diseases in calves
S100B in cerebrospinal fluid (CSF-S100B) was measured in calves with 20 neurologic and 21 non-neurologic diseases to clarify its utility as a biomarker for neurologic diseases. The median CSF-S100B value in the neurologic disease group (43.0 ng/ml) was significantly higher than that in the non-neurologic disease group (10.2 ng/ml). As CSF-S100B levels in calves with neurologic diseases widely d...
متن کاملCerebrospinal fluid nerve growth factor and total protein concentration in the children with meningitis
Meningitis is one of the most common infectious cerebral nervous system (CNS), defined as an inflammation of the meninges. It is clinically categorized into a chronic and acute based on the acuity of symptoms. Vomiting, bulging fontanel and fever are the main symptoms in the patients with meningitis. Bacterial meningitis is a severe, potentially life-threatening infection that is associated wit...
متن کاملCan S100B Predict Cerebral Vasospasms in Patients Suffering from Subarachnoid Hemorrhage?
BACKGROUND Protein S100B has proven to be a useful biomarker for cerebral damages. Increased levels of serum and cerebrospinal fluid (CSF) S100B have been shown in patients suffering subarachnoid hemorrhage (SAH), severe head injury and stroke. In patients with SAH, the course of S100B levels has been correlated with neurological deficits and outcome. Cerebral vasospasm is a major contributor t...
متن کاملAssociation between Cerebrospinal Fluid S100B Protein and Neuronal Damage in Patients with Central Nervous System Infections
PURPOSE S100B protein is widely used as a measure of glial activity or damage in several brain conditions. Central nervous system (CNS) infections can cause neurological sequelae because of parenchyma invasion. It is difficult to predict further neuronal damage in the CNS infection. The present study is aimed to evaluate the role of the cerebrospinal fluid (CSF) S100B protein as an indicator of...
متن کاملPotential Use of Amniotic Membrane Derived Scaffold for Cerebrospinal Fluid Applications
Scaffolds derived from decellularized tissues provide a natural microenvironment for cell culture. Embryonic cerebrospinal fluid (e-CSF) contains factors which play vital roles in development of the nervous system. This research was aimed to survey the effect of Wistar rat e-CSF on neural differentiation of bone marrow derived mesenchymal stem cells (BM-MSCs) cultured on the human amniotic memb...
متن کامل